📋 Indications & Clinical Dosage
*Severe hypertension, in addition to a diuretic and a beta- blocker:*
Adult: Initially 5 mg daily in 1–2 divided doses, then increased in steps of 5–10 mg, increased at intervals of at least 3 days; max. 100 mg per day.
Elderly: Initially 2.5 mg daily in 1–2 divided doses, then increased in steps of 5–10 mg, increased at intervals of at least 3 days; max. 100 mg per day.
⚠️ Precautions & Warnings
Acute porphyrias, after myocardial infarction (until stabilised), angina, renal impairment
⚠️ Adverse Reactions / Side Effects
GI disorder, fluid retention, oedema, sodium retention, hair changes, pericardial disorders, pericarditis, tachycardia, breast tenderness, pleural effusion, weight increased. Rare: Leucopenia, skin reactions, Stevens- Johnson syndrome, thrombocytopenia, Angina pectoris