🩺 ANTIHISTAMINES FOR SYSTEMIC USE 🏷️ Loratadine metabolite
👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Tab 5 mg — 10 Rs.144 Rs.170 syrup 0.5 mg

📋 Indications & Clinical Dosage

*Symptomatic relief of allergy such as allergic rhinitis, urticaria, chronic idiopathic urticaria:* Adult & Children above 12 yrs: 5 mg once daily. Children 1-5 yrs: 1.25 mg once daily; 6-11 yrs: 2.5 mg once daily.

⛔ Contraindications

Acute porphyrias, hypersensitivity to loratadine.

⚠️ Precautions & Warnings

Severe renal impairment, epilepsy

⚠️ Adverse Reactions / Side Effects

Headache, drowsiness, dizziness, dry mouth, antimuscarinic effects, blurred vision, GI disturbances, psychomotor impairment, urinary retention. Rare:Anaphylaxis, angioedema, angle-closure glaucoma

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
Caution advised
Lactation / Breastfeeding:
Caution advised

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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