📋 Indications & Clinical Dosage
*Painful and restricted mobility condition of degenerative and traumatic knee and other synovial joints:*
Adults: One injection by intra-articular injection once weekly for 3-5 consecutive weeks. Course may be repeated at not less than 6 months interval.
Children: Not recommended.
💊 Mode of Administration
Intra-articular: Injected directly into the knee joint.
⛔ Contraindications
Infection or skin disease at injection site.
🔄 Drug Interactions
Other intra-articular preps.
⚠️ Adverse Reactions / Side Effects
Transient pain and swelling at injection site, local irritation
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
Caution advised
Lactation / Breastfeeding:
Caution advised
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.