ADMIT (SITAGLIPTIN) Price

Dosage Form	Reg. No	Pack Size	Trade Price (TP)	Maximum Retail Price (MRP)
Tab 25 mg	—	14	—	Rs.195.50 230.00
Tab 50 mg	—	14	Rs.328.74	Rs.361.25
Tab 100 mg	—	14	Rs.462.55	Rs.508.30
Tab 1000 mg	—	14	—	Rs.358.90 394.40

📋 Indications & Clinical Dosage

*Type 2 diabetes mellitus as monotherapy or in combination with metformin or a sulfonylurea, or pioglitazone (duel therapy), and in combination with both metformin and a sulfonylurea (triple therapy) to achieve adequate glycaemic control:* Adult: 100 mg once daily *Type 2 diabetes mellitus in combination with both metformin and pioglitazone, or in combination with insulin (withor without metformin) when insulin alone fails to provide adequate glycaemic control:* Adult: 100 mg once daily Dose of concomitant sulfonylurea or insulin may need to be reduced. Children: Not recommended.

⛔ Contraindications

Ketoacidosis, severe renal impairment.

⚠️ Precautions & Warnings

Elderly, renal impairment reduce dose to 50 mg once daily if eGFR 30-50 ml/minute/1.73m2, reduce dose to 25mgonce daily if eGFR less than 30 ml/minute/1.73m2.

🔄 Drug Interactions

Digoxin

⚠️ Adverse Reactions / Side Effects

GI disturbances, nasopharyngitis, pain, peripheral oedema, upper respiratory tract infection, anorexia, dizziness, drowsiness, dry mouth, headache, hypoglycaemia, cutaneous vasculitis, pancreatitis (discontinue) rash, Stevens-Johnson syndrome, osteoarthritis.

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:

Contraindicated in pregnancy.

Lactation / Breastfeeding:

Not recommended.

📚 Official Regulatory & Clinical References

Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.